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PUBLICATIONS

  1. S Sivaprasad, S Patra, J DaCosta, T Adewoyin, O Shona, E Pearce, NV Chong. A pilot study on the combination treatment of reduced-fluence photodynamic therapy, intravitreal ranibizumab, intravitreal dexamethasone and oral minocycline for neovascular age-related macular degeneration. Ophthalmologica, 2011; 225(4): 200-6.
  2. P Charbel Issa, NV Chong, HP Scholl. The significance of the comlement system for the pathogenesis of age-related macular degeneration. Graefes Arch Clin Exp Ophthal 2011; 249: 163-74. Reprint
  3. C Kiire, S Sivaprasad, V Chong. Subthreshold micropulse laser therapy for retinal disorders. Retina Today Jan/Feb 2011 Reprint
  4. I Mitrut, A Verma, S Madill, RT Smith, NV Chong. Color contrast and drusen area. Ophthalmology. 2010 Jun;117(6):1280-1. Reprint
  5. E Pearce, S Sivaprasad, NV Chong. Comparison of location and stability of fixation in patients with neovascular age-related macular degeneration treated with or without Ranibizumab. Eye 2010 Nov 19. Epub. Reprint
  6. JR Evans, V Sivagnanavel, V Chong.  Radiotherapy for neovascular age-related macular degeneration. Cochrane Database Syst Rev. 2010 May 12;5:CD004004. Review. Reprint
  7. JA Haller, F Bandello, R Belfort Jr, et al., OZURDEX GENEVA Study Group. Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion. Ophthalmology. 2010 Jun;117(6):1134-1146.e3. Epub 2010 Apr 24. Reprint
  8. A Malik, EC Fletcher, V Chong, J Dasan. Local anesthesia for cataract surgery. J Cataract Refract Surg. 2010 Jan;36(1):133-52.
  9. S Jyothi, HR Chowdhury, V Chong, S Sivaprasad. Anti-VEGF therapy for choroidal neovascularisation previously treated with photodynamic therapy. Eye (Lond). 2009 Nov 6. Reprint
  10. B Gupta, M Elagouz, D McHugh, V Chong, S Sivaprasad. Micropulse diode laser photocoagulation for central serous chorio-retinopathy. Clin Experiment Ophthalmol. 2009 Nov;37(8):801-5.
  11. J Khan, V Chong. Optical coherence tomography study of adult vitelliform macular detachment in a patient with basal laminar drusen. Int Ophthalmol. 2009 Dec 1.
  12. SP Harding, K Tomlin, BC Reeves, et al. VPDT cohort study group. Verteporfin photodynamic therapy cohort study: report 1: effectiveness and factors influencing outcomes. Ophthalmology. 2009 Dec;116(12):e1-8. Reprint
  13. NV Chong. Should avastin be used to treat age-related macular degeneration in the NHS? – No. Eye 2009; 23: 1250-3 Reprint
  14. J Figueria, J Khan, S Nunes, S Sivaprasad, A Rosa, JF de Abreu, JG Cunha-Vaz, NV Chong. Prospective randomised controlled trial comparing sub-threshold micropulse diode laser photocoagulation and conventional green laser for clinically significant diabetic macular oedema. Br J Ophthalmol. 2009 Oct;93(10):1341-4.  Epub 2008 Dec 3. Reprint
  15. W Amoaku et al, Ranibizumab: The clinician's guide to commencing, continuing, and discontinuing treatment. Eye (Lond). 2009 Nov;23(11):2140-2. Epub 2008 Aug 1 Reprint
  16. EC Fletcher, RJ Lade, T Adewoyin, NV Chong. Computerized model of cost-utility analysis for treatment of age-related macular degeneration. Ophthalmology. 2008 Dec;115(12):2192-8. Epub 2008 Oct 18. Reprint
  17. EC Fletcher, NV Chong. Looking beyond Lucentis on the management of macular degeneration. Eye 2008 1-9. Reprint
  18. HP Scholl, P Charbel Issa, M Walier, S Janzer, B Pollok-Kopp, F Börncke, LG Fritsche, NV Chong, R Fimmers, T Wienker, FG Holz, BH Weber, M Oppermann. Systemic complement activation in age-related macular degeneration. PLoS ONE. 2008 Jul 2;3(7):e2593. Reprint
  19. R Wong, J Khan, T Adewoyin, S Sivaprasad, GB Arden, V Chong. The ChromaTest, a digital color contrast sensitivity analyzer, for diabetic maculopathy: a pilot study. BMC Ophthalmol. 2008 Aug 17;8:15. Reprint
  20. JR Yates, T Sepp, BK Matharu, et al, Genetic factors in AMD Study Group. Complement C3 variant and the risk of age-related macular degeneration. New England Journal of Medicine. 2007 Aug 9; 357(6):553-61. Reprint
  21. S Sivaprasad, T Adewoyin, TA Bailey, SS Dandekar, S Jenkins, AR Webster, NV Chong. Estimation of systemic C3 activity in Age-related Macular Degeneration. Archives of Ophthalmology 2007;125(4):515-9 Reprint
  22. C Turney, NHV Chong RA Alexander, CR Hogg, L Fleming, D Flack, KC Barnett, AC Bird, GE Holder, PJ Luthert. Pathological and electrophysiological features of a canine cone-rod dystrophy in the miniature longhaired dachshund. Investigative Ophthalmology & Visual Science 2007 Sep;48:4240-9. Reprint
  23. J Khan, V Chong. Sudden visual loss. Lancet. 2007 Aug 18;370(9587):590. 
  24. N Patel, T Adewoyin, NV Chong. Age-related macular degeneration: a perspective on genetic studies. Eye 2007 May 11-Epub Reprint
  25. J Khan, V Chong. Two retinal vein occlusions in a patient with venous tortuosity at the optic disc. Graefes Arch Clin Exp Ophthalmol. 2007 Feb;245(2):313-4. Reprint
  26. NV Chong, T Adewoyin. Intravitreal injection – Balancing the risks. Eye 2007 Mar. 21(3): 313-6 Reprint
  27. KY Chau, S Sivaprasad, N Patel, TA Donaldson, PJ Luthert, NV Chong. Plasma levels of Matrix Metalloproteinase- 2 and 9 (MMP-2 and MMP-9) in Age-related Macular Degeneration. Eye 2007 – Epub Reprint
  28. NV Chong. Perimacular retinal folds and nonaccidental injury – Yes, No or May Be? Eye 2007 Jan; 21(1):3-4 Reprint
  29. R Sandhu, S Sivaprasad, SP Shah, T Adewoyin, NV Chong. Pulsatile ocular blood flow in asymmetric age-related macular degeneration. Eye 2007 Apr 21(4):506-11 Reprint
  30. RT Smith, J Chan, M Busuoic, V Sivagnanavel, AC Bird, NV Chong. Autofluorescence characteristics of early, atrophic, and high-risk fellow eyes in age-related macular degeneration. Investigative Ophthalmology & Visual Science 2006; 47(12): 5495-504 Reprint
  31. U Chakravarthy, G Soubrane, F Bandello, V Chong, et. al Evolving European guidance on the medical management of neovascular age related macular degeneration Br J Ophthalmol 2006; 90: 1188-96 Reprint
  32. EC Fletcher, V Chong. The impact of national diabetic retinopathy screening on ophthalmology: the need for urgent planning. Eye. 2006 Dec; 20(12):1424-5 Reprint
  33. J Khan, V Chong So what do you think of this laser eye surgery, doc? Student BMJ May 2006 Reprint
  34. V Chong. Molecular therapies for AMD. Optician 2006 June 23 6057 Reprint
  35. S Sivaprasad, NV Chong. The complement system and age-related macular degeneration. Eye 2006 Aug; 20(8):867-72 Reprint
  36. S Sivaprasad, WL Membrey, V Sivagnanavel, JG Gonzalez, DT Liu, WM Chan, DS Lam, H Jackson, NV Chong. Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese Eye. 2006 Aug 20(8);923-6 Reprint
  37. S Sivaprasad, NV Chong, TA Bailey. Serum Elastin-Derived Peptides in Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2005 Sep;46(9):3046-3051. Reprint
  38. N Patel, M Ohbayashi M, AK Nugent, K Ramchand, M Toda, KY Chau, C Bunce, A Webster, AC Bird, SJ Ono, V Chong. Circulating anti-retinal antibodies as immune markers in AMD. Immunology. 2005 Jul;115(3):422-30. Reprint
  39. NHV Chong, J Keonin, PJ Luthert, CI Frennesson, DM Weingeist, RL Wolf, RF Mullins, GS Hageman. Decreased thickness and integrity of the macular elastic layer of Bruch’s membrane corresponds to the distribution of lesions associated with age-related macular degeneration. American Journal of Pathology – 2005 166(1): 241-51 Reprint
  40. J Khan, V Chong. Two retinal vein occlusions in a patient with venous tortuosity at the optic disc. Graefes Archives of Clinical Experimental Ophthalmology 2005; 1-2 Reprint
  41. S Sivaprasad, TA Bailey, V Chong. Bruch's membrane and the vascular intima: is there a common basis for age-related changes and disease? Clinical and Experimental Ophthalmology 2005 Oct;33(5):518-2 Reprint
  42. S Sivaprasad, CJ Hammond, H Jackson, NH Chong. Proportion of treatable subtypes of choroidal neovascular membranes in Age-Related Macular Degeneration International Congress series 2005; 1982;312-316
  43. N Patel, P Riordan-Eva, V Chong. Persistent visual loss after retinochoroidal infarction in pregnancy-induced hypertension and disseminated intravascular coagulation. Journal of Neuroophthalmology 2005 Jun;25(2):128-30.
  44. S Jain, S Hamada, WL Membrey, V Chong. Screening for age-related macular degeneration using nonstereo digital fundus photographs. Eye. 2005 May 13 Epub Reprint
  45. V Sivagnanavel, RT Smith, GB Lau, J Chan, C Donaldson, NV Chong. An interinstitutional comparative study and validation of computer aided drusen quantification. British Journal of Ophthalmology – 2005; 89:554-557 Reprint
  46. S Sivaprasad, NV Chong. Vitamins and age-related macular degeneration. Current Medical Literature – Clinical Nutrition, Spring 2005
  47. S Hamada, S Jain, V Sivagnanavel, N Patel, NV Chong. Drusen classification in bilateral drusen and fellow eye of exudative AMD. Eye – 2005; Mar 4 Epub Reprint
  48. EH Hughes, J Khan, N Patel, S Kashani, NV Chong. In vivo demonstration of the anatomic differences between classic and occult choroidal neovascularisation using optical coherence tomography. Americian Journal of Ophthalmology –2005;139:344-6
  49. RI Angunawela, TH Williamson, MAJ Khan, V Chong. Choroidal translocation with a pedicle following excision of a type 1 choroidal neovascular membrane. British Journal of Ophthalmology – 2005; 89: 386 Reprint
  50. HP Scholl, NHV Chong, AG Robson, GE Holder, AT Moore, AC Bird. Fundus autofluorescence in patients with leber congenital amaurosis. Investigative Ophthalmology & Visual Science – 2004 45(8):2747-52 Reprint
  51. S Amin, NHV Chong, TA Bailey, J Zhang, C Knupp, ME Cheetham, J Greenwood, PJ Luthert. Modulation of sub-RPE deposits in vitro; a potential model for age-related macular degeneration. Investigative Ophthalmology & Visual Science – 2004 45(5):1281-8 Reprint
  52. V Sivagnanavel, J Evans, Z Ockrim, V Chong. Radiotherapy for neovascular age-related macular degeneration (Cochrane Review). Cochrane Database Syst Rev. 2004 Oct 18;(4):CD004004. Review Reprint
  53. N Patel, G Bowler, T Adeniji, AK Nugent, D Lake, S Seswathi, NV Chong. Cataract surgery in patients with diabetes and age-related macular degeneration. Comprehensive Ophthalmology Update – 2004 5(6): 275-282
  54. S Sivaprasad, NV Chong. Vitamins and age-related macular degeneration. Current Medical Literature – Ophthalmology, Spring 2004
  55. NHV Chong, A Kvanta, S Seregard, AC Bird, PJ Luthert, B Steen. TIMP-3 mRNA is not overexpressed in Sorsby fundus dystrophy. Am Journal of Ophthal 2003; 136: 954-5. Reprint
  56. C Knupp, NHV Chong, PM Munro, PJ Luthert, JM Squire. Analysis of the Collagen VI Assemblies Associated with Sorsby's Fundus Dystrophy. Journal of Structural Biology 2002; 137(1-2):31-40 Reprint
  57. TA Bailey, RA Alexander, SR Dubovy, PJ Luthert, NHV Chong. Measurement of TIMP-3 expression and Bruch’s membrane thickness in human macula – Experimental Eye Research 2001; 73(6):851-8 Reprint
  58. GS Hageman, PJ Luthert, NHV Chong, DH Anderson, RF Mullins. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Progress in Retinal and Eye Research 2001; 20(6): 705-732 Reprint
  59. PE Stanga, SM Downes, RM Ahuja, NHV Chong, R Antcliff, AC Reck, AC Bird. Comparison of optical coherence tomography and fluorescein angiography in assessing macular edema in retinal dystrophies: preliminary results. International Ophthalmology 2001; 23(4-6):321-5.
  60. PE Stanga, NHV Chong, AC Reck, AJ Hardcastle, GE Holder. Optical coherence tomography and electrophysiology in X-linked juvenile retinoschisis associated with a novel mutation in the XLRS1 gene. Retina 2001;21(1):78-80
  61. NHV Chong, RA Alexander, T Gin, AC Bird, PJ Luthert. TIMP-3, collagen and elastin immunohistochemistry and histopathology of Sorsby’s fundus dystrophy. Investigative Ophthalmology & Visual Science 2000; 41: 898-902 Reprint
  62. CS Sethi, TA Bailey, PJ Luthert, NHV Chong. Matrix metalloproteinase biology applied to vitreoretinal disorders British Journal of Ophthalmology, 2000, 84; 654-66. Reprint
  63. NHV Chong, RA Alexander, KC Barnett, AC Bird, PJ Luthert. An immunohistochemical study of an autosomal dominant feline rod / cone dysplasia (Rdy cats). Experimental Eye Research 1999; 68(1); 51-7 Reprint
  64. NHV Chong, RA Alexander, L Waters, KC Barnett, AC Bird, PJ Luthert. Repeated intravitreal injections of ciliary neurotrophic factor lead to long-term photoreceptor cells survival in hereditary retinal degeneration. Investigative Ophthalmology & Visual Science 1999; 40: 1298-1305 Reprint
  65. NHV Chong, AC Bird. Current and future management of inherited outer retinal dystrophies. British Journal of Ophthalmology, 1999, 83; 120-22. Reprint
  66. NHV Chong, AC Bird. Alternative therapies in exudative age related macular degeneration. British Journal of Ophthalmology, 1998, 82; 1441-43. Reprint
  67. PJ Luthert, NHV Chong. Photoreceptor rescue. Eye 1998; 12: 591-596.
  68. CBO Yu, NHV Chong, RH Caesar, MG Boodhoo, RW Condon. Long term results of combined cataract and glaucoma surgery vs trabeculectomy alone in low risk patients. Journal of Cataract and Refractive Surgery 1996; 22: 352-57
  69. SJ Talks, NHV Chong, JM Gibson, PM Dodson. Fibrinogen, cholesterol and smoking as risk factors for non arteritic anterior ischaemic optic neuropathy. Eye 1995; Vol 9: 85 – 8 (Spencer Walker Prize winner)
  70. SJ Talks, NHV Chong, JM Gibson, IR Francis. Visual acuity and pupillary reactions after peribulbar anaesthesia. British Journal of Ophthalmology 1994 (1), 78, 41-3
  71. NHV Chong, RK Aggarwal, P Shah, PI Murray. Is measuring intraocular pressure necessary on the first post-operative day following uncomplicated cataract surgery? Eye 1994; 8:115-6
  72. NHV Chong, SJ Talks, JM Gibson. Eczema and Eye Rubbing - A case of pupillary entrapment of P/C IOL. European J Implant Refractive Surgery 1994; Vol 6: 211-3
  73. NHV Chong. Glaucoma induced by steroids. British Medical Journal 1994; 309: 343
  74. NV Chong, PI Murray. Pen torch test in patients with unilateral red eye. British Journal of General Practice 1993 (6), Vol 43: 259
  75. NHV Chong, JR Murdoch. Is ophthalmic therapy often overlooked in hospital wards? Journal of the Royal Society of Medicine 1993 (10); Vol 86: 569-70
  76. NHV Chong, JR Murdoch, M Cleary. Horizontal gaze palsy associated with pontine haemorrhage. British Orthoptic Journal 1993; 50: 62-3
  77. RK Aggarwal, T Potamitis, NHV Chong, M Guarro, P Shah, S Kheterpal. Extensive visual loss associated with topical facial steroids Eye 1993; 7, 664-6

Books and Book Chapters

  1. NV Chong, S Sivaprasad, RL Smith, “Retinal Physiology and Biology” in “Retinal Pharmacotherapy” Ed Mieler, Farah, Rodrigues, Nguyen, Elsevier, 2010
  2. NV Chong, “Optical coherence tomography in exudative age-related macular degeneration” in “Diagnostic technologies in Ophthalmology” Ed Lois, Hossain, Bentham, 2010
  3. NV Chong, EC Fletcher, Retinal Diseases Chapter in “General Ophthalmology – 18th Ed” Ed Vaughan, Asbury, Riordan-Eva. Appleton and Lange, 2010
  4. NV Chong, Laser in Ophthalmology Chapter in “General Ophthalmology – 18th Ed” Ed Vaughan, Asbury, Riordan-Eva. Appleton and Lange, 2010
  5. NV Chong, EC Fletcher, Retinal Diseases Chapter in “General Ophthalmology – 17th Ed” Ed Vaughan, Asbury, Riordan-Eva. Appleton and Lange, 2007
  6. NV Chong, Laser in Ophthalmology Chapter in “General Ophthalmology – 17th Ed” Ed Vaughan, Asbury, Riordan-Eva. Appleton and Lange, 2007
  7. NHV Chong, J Khan, M Spalton. Medical Retina (4 Chapters) in “Colour Atlas of Clinical Ophthalmology – 3rd Ed” Ed Spalton, Hitching, Hunter, Tan. Butterworth Heinemann, - 2005 (BMJ Book of the Year 2005)
  8. NV Chong. Laser in Ophthalmology in “General Ophthalmology – 16th Ed” Ed Vaughan, Asbury, Riordan-Eva. Appleton and Lange, 2003
  9. NHV Chong. Visual Diagnosis in Eye Diseases – Merit Publishing, London 2002
  10. NHV Chong, SM Downes, GM Freeman, K Sehmi, GE Holder, AC Bird. The Medical Retina - Moorfields CD-ROM. BMJ Books, London 1999
  11. NHV Chong. Clinical Ocular Physiology - an introductory text. Butterworth Heinemann, Oxford 1997
  12. SM Downes, NHV Chong, AC Bird. Ophthalmologist's Perspective in "Ocular Molecular Biology Protocols" Ed PE Rakoczy. Humana Press, New Jersey 2000